| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| eno | kdsA | SRM1_01149 | SRM1_01148 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.881 |
| eno | lpxA | SRM1_01149 | SRM1_01141 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.768 |
| eno | lpxB | SRM1_01149 | SRM1_01142 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.731 |
| eno | lpxD_1 | SRM1_01149 | SRM1_01139 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.606 |
| eno | pyrG | SRM1_01149 | SRM1_01147 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.945 |
| kdsA | eno | SRM1_01148 | SRM1_01149 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.881 |
| kdsA | kdsB | SRM1_01148 | SRM1_04121 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.930 |
| kdsA | kdsC | SRM1_01148 | SRM1_00908 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.999 |
| kdsA | kdsD_1 | SRM1_01148 | SRM1_00909 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Arabinose 5-phosphate isomerase KdsD. | 0.997 |
| kdsA | lpxA | SRM1_01148 | SRM1_01141 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.912 |
| kdsA | lpxB | SRM1_01148 | SRM1_01142 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.914 |
| kdsA | lpxC | SRM1_01148 | SRM1_04715 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.886 |
| kdsA | lpxD_1 | SRM1_01148 | SRM1_01139 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.907 |
| kdsA | pyrG | SRM1_01148 | SRM1_01147 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.917 |
| kdsA | waaA | SRM1_01148 | SRM1_00542 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.881 |
| kdsB | kdsA | SRM1_04121 | SRM1_01148 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.930 |
| kdsB | kdsC | SRM1_04121 | SRM1_00908 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.999 |
| kdsB | kdsD_1 | SRM1_04121 | SRM1_00909 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Arabinose 5-phosphate isomerase KdsD. | 0.935 |
| kdsB | lpxA | SRM1_04121 | SRM1_01141 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.919 |
| kdsB | lpxB | SRM1_04121 | SRM1_01142 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.917 |