| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysD | cysG | SRM1_00924 | SRM1_03423 | Sulfate adenylyltransferase subunit 2. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.854 |
| cysD | cysJ_1 | SRM1_00924 | SRM1_00844 | Sulfate adenylyltransferase subunit 2. | Sulfite reductase [NADPH] flavoprotein alpha-component. | 0.548 |
| cysD | cysNC | SRM1_00924 | SRM1_00926 | Sulfate adenylyltransferase subunit 2. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| cysD | sbnA | SRM1_00924 | SRM1_01253 | Sulfate adenylyltransferase subunit 2. | Putative siderophore biosynthesis protein SbnA. | 0.500 |
| cysE_1 | cysNC | SRM1_00301 | SRM1_00926 | Serine acetyltransferase. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.549 |
| cysE_1 | metC | SRM1_00301 | SRM1_03080 | Serine acetyltransferase. | Cystathionine beta-lyase. | 0.406 |
| cysE_1 | metZ | SRM1_00301 | SRM1_01998 | Serine acetyltransferase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.406 |
| cysE_1 | sbnA | SRM1_00301 | SRM1_01253 | Serine acetyltransferase. | Putative siderophore biosynthesis protein SbnA. | 0.811 |
| cysE_2 | cysNC | SRM1_04658 | SRM1_00926 | Serine acetyltransferase. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.549 |
| cysE_2 | metC | SRM1_04658 | SRM1_03080 | Serine acetyltransferase. | Cystathionine beta-lyase. | 0.406 |
| cysE_2 | metZ | SRM1_04658 | SRM1_01998 | Serine acetyltransferase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.491 |
| cysE_2 | sbnA | SRM1_04658 | SRM1_01253 | Serine acetyltransferase. | Putative siderophore biosynthesis protein SbnA. | 0.811 |
| cysG | cysD | SRM1_03423 | SRM1_00924 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate adenylyltransferase subunit 2. | 0.854 |
| cysG | cysJ_1 | SRM1_03423 | SRM1_00844 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfite reductase [NADPH] flavoprotein alpha-component. | 0.807 |
| cysG | cysNC | SRM1_03423 | SRM1_00926 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.967 |
| cysG | gltB | SRM1_03423 | SRM1_00466 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Glutamate synthase [NADPH] large chain precursor. | 0.779 |
| cysG | metC | SRM1_03423 | SRM1_03080 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Cystathionine beta-lyase. | 0.552 |
| cysG | metZ | SRM1_03423 | SRM1_01998 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.818 |
| cysG | moaD | SRM1_03423 | SRM1_01007 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Molybdopterin synthase sulfur carrier subunit. | 0.442 |
| cysG | sbnA | SRM1_03423 | SRM1_01253 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative siderophore biosynthesis protein SbnA. | 0.573 |