| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fumA | leuA | SRM1_04395 | SRM1_04638 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.412 |
| fumA | ybdG | SRM1_04395 | SRM1_01423 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Miniconductance mechanosensitive channel YbdG. | 0.406 |
| leuA | fumA | SRM1_04638 | SRM1_04395 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.412 |
| leuA | mepM_1 | SRM1_04638 | SRM1_04637 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | Murein DD-endopeptidase MepM. | 0.694 |
| leuA | xseA | SRM1_04638 | SRM1_04636 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.694 |
| leuA | ybdG | SRM1_04638 | SRM1_01423 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | Miniconductance mechanosensitive channel YbdG. | 0.694 |
| mepM_1 | leuA | SRM1_04637 | SRM1_04638 | Murein DD-endopeptidase MepM. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.694 |
| mepM_1 | xseA | SRM1_04637 | SRM1_04636 | Murein DD-endopeptidase MepM. | Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.898 |
| mepM_1 | ybdG | SRM1_04637 | SRM1_01423 | Murein DD-endopeptidase MepM. | Miniconductance mechanosensitive channel YbdG. | 0.694 |
| mscL | mscS_2 | SRM1_04939 | SRM1_04356 | Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Small-conductance mechanosensitive channel. | 0.474 |
| mscL | ybdG | SRM1_04939 | SRM1_01423 | Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Miniconductance mechanosensitive channel YbdG. | 0.402 |
| mscS_2 | mscL | SRM1_04356 | SRM1_04939 | Small-conductance mechanosensitive channel. | Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.474 |
| mscS_2 | ybdG | SRM1_04356 | SRM1_01423 | Small-conductance mechanosensitive channel. | Miniconductance mechanosensitive channel YbdG. | 0.505 |
| rhlE_1 | ybdG | SRM1_01424 | SRM1_01423 | ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | Miniconductance mechanosensitive channel YbdG. | 0.563 |
| xseA | leuA | SRM1_04636 | SRM1_04638 | Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.694 |
| xseA | mepM_1 | SRM1_04636 | SRM1_04637 | Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | Murein DD-endopeptidase MepM. | 0.898 |
| xseA | ybdG | SRM1_04636 | SRM1_01423 | Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | Miniconductance mechanosensitive channel YbdG. | 0.698 |
| ybdG | fumA | SRM1_01423 | SRM1_04395 | Miniconductance mechanosensitive channel YbdG. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.406 |
| ybdG | leuA | SRM1_01423 | SRM1_04638 | Miniconductance mechanosensitive channel YbdG. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.694 |
| ybdG | mepM_1 | SRM1_01423 | SRM1_04637 | Miniconductance mechanosensitive channel YbdG. | Murein DD-endopeptidase MepM. | 0.694 |