| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | bkdB | SRM1_00516 | SRM1_03245 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 0.700 |
| aceF | gltB | SRM1_00516 | SRM1_00466 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glutamate synthase [NADPH] large chain precursor. | 0.929 |
| aceF | icd_1 | SRM1_00516 | SRM1_03435 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Isocitrate dehydrogenase [NADP]. | 0.479 |
| aceF | lpdG | SRM1_00516 | SRM1_01613 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.998 |
| aceF | lpdV | SRM1_00516 | SRM1_03246 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyl dehydrogenase. | 0.999 |
| aceF | sucA | SRM1_00516 | SRM1_01611 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component. | 0.994 |
| aceF | sucB | SRM1_00516 | SRM1_01612 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.799 |
| aceF | sucC | SRM1_00516 | SRM1_01614 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.991 |
| aceF | sucD | SRM1_00516 | SRM1_01615 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.987 |
| bkdB | aceF | SRM1_03245 | SRM1_00516 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.700 |
| bkdB | gltB | SRM1_03245 | SRM1_00466 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Glutamate synthase [NADPH] large chain precursor. | 0.929 |
| bkdB | icd_1 | SRM1_03245 | SRM1_03435 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Isocitrate dehydrogenase [NADP]. | 0.479 |
| bkdB | lpdG | SRM1_03245 | SRM1_01613 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Dihydrolipoamide dehydrogenase. | 0.992 |
| bkdB | lpdV | SRM1_03245 | SRM1_03246 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Dihydrolipoyl dehydrogenase. | 0.999 |
| bkdB | sucA | SRM1_03245 | SRM1_01611 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 2-oxoglutarate dehydrogenase E1 component. | 0.988 |
| bkdB | sucC | SRM1_03245 | SRM1_01614 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.940 |
| bkdB | sucD | SRM1_03245 | SRM1_01615 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.883 |
| gltB | aceF | SRM1_00466 | SRM1_00516 | Glutamate synthase [NADPH] large chain precursor. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.929 |
| gltB | bkdB | SRM1_00466 | SRM1_03245 | Glutamate synthase [NADPH] large chain precursor. | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 0.929 |
| gltB | icd_1 | SRM1_00466 | SRM1_03435 | Glutamate synthase [NADPH] large chain precursor. | Isocitrate dehydrogenase [NADP]. | 0.982 |