| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bkdA1 | bkdA2 | SRM1_03243 | SRM1_03244 | 2-oxoisovalerate dehydrogenase subunit alpha. | 2-oxoisovalerate dehydrogenase subunit beta. | 0.999 |
| bkdA1 | lpd3 | SRM1_03243 | SRM1_05821 | 2-oxoisovalerate dehydrogenase subunit alpha. | Dihydrolipoyl dehydrogenase 3. | 0.889 |
| bkdA1 | lpdG | SRM1_03243 | SRM1_01613 | 2-oxoisovalerate dehydrogenase subunit alpha. | Dihydrolipoamide dehydrogenase. | 0.935 |
| bkdA1 | lpdV | SRM1_03243 | SRM1_03246 | 2-oxoisovalerate dehydrogenase subunit alpha. | Dihydrolipoyl dehydrogenase. | 0.999 |
| bkdA1 | sthA | SRM1_03243 | SRM1_03773 | 2-oxoisovalerate dehydrogenase subunit alpha. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.760 |
| bkdA1 | sucB | SRM1_03243 | SRM1_01612 | 2-oxoisovalerate dehydrogenase subunit alpha. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.974 |
| bkdA2 | bkdA1 | SRM1_03244 | SRM1_03243 | 2-oxoisovalerate dehydrogenase subunit beta. | 2-oxoisovalerate dehydrogenase subunit alpha. | 0.999 |
| bkdA2 | lpd3 | SRM1_03244 | SRM1_05821 | 2-oxoisovalerate dehydrogenase subunit beta. | Dihydrolipoyl dehydrogenase 3. | 0.979 |
| bkdA2 | lpdG | SRM1_03244 | SRM1_01613 | 2-oxoisovalerate dehydrogenase subunit beta. | Dihydrolipoamide dehydrogenase. | 0.987 |
| bkdA2 | lpdV | SRM1_03244 | SRM1_03246 | 2-oxoisovalerate dehydrogenase subunit beta. | Dihydrolipoyl dehydrogenase. | 0.999 |
| bkdA2 | sthA | SRM1_03244 | SRM1_03773 | 2-oxoisovalerate dehydrogenase subunit beta. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.918 |
| bkdA2 | sucA | SRM1_03244 | SRM1_01611 | 2-oxoisovalerate dehydrogenase subunit beta. | 2-oxoglutarate dehydrogenase E1 component. | 0.947 |
| bkdA2 | sucB | SRM1_03244 | SRM1_01612 | 2-oxoisovalerate dehydrogenase subunit beta. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.996 |
| bkdA2 | sucC | SRM1_03244 | SRM1_01614 | 2-oxoisovalerate dehydrogenase subunit beta. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.591 |
| bkdA2 | sucD | SRM1_03244 | SRM1_01615 | 2-oxoisovalerate dehydrogenase subunit beta. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.513 |
| cat1 | sucA | SRM1_00169 | SRM1_01611 | Succinyl-CoA:coenzyme A transferase. | 2-oxoglutarate dehydrogenase E1 component. | 0.469 |
| cat1 | sucB | SRM1_00169 | SRM1_01612 | Succinyl-CoA:coenzyme A transferase. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.964 |
| cat1 | sucC | SRM1_00169 | SRM1_01614 | Succinyl-CoA:coenzyme A transferase. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.987 |
| cat1 | sucD | SRM1_00169 | SRM1_01615 | Succinyl-CoA:coenzyme A transferase. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.985 |
| lpd3 | bkdA1 | SRM1_05821 | SRM1_03243 | Dihydrolipoyl dehydrogenase 3. | 2-oxoisovalerate dehydrogenase subunit alpha. | 0.889 |