| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL28506.1 | cysE_1 | SRM1_01845 | SRM1_00301 | Haloacid dehalogenase-like hydrolase. | Serine acetyltransferase. | 0.957 |
| CEL28506.1 | cysE_2 | SRM1_01845 | SRM1_04658 | Haloacid dehalogenase-like hydrolase. | Serine acetyltransferase. | 0.960 |
| CEL28506.1 | glyA2_1 | SRM1_01845 | SRM1_04928 | Haloacid dehalogenase-like hydrolase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.980 |
| CEL28506.1 | glyA2_2 | SRM1_01845 | SRM1_05308 | Haloacid dehalogenase-like hydrolase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.980 |
| CEL28506.1 | hom | SRM1_01845 | SRM1_01082 | Haloacid dehalogenase-like hydrolase. | Homoserine dehydrogenase. | 0.962 |
| CEL28506.1 | serB_1 | SRM1_01845 | SRM1_00558 | Haloacid dehalogenase-like hydrolase. | Phosphoserine phosphatase. | 0.976 |
| CEL28506.1 | serC_1 | SRM1_01845 | SRM1_04024 | Haloacid dehalogenase-like hydrolase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.983 |
| CEL28506.1 | thrB | SRM1_01845 | SRM1_00117 | Haloacid dehalogenase-like hydrolase. | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. | 0.977 |
| CEL28506.1 | thrC | SRM1_01845 | SRM1_01083 | Haloacid dehalogenase-like hydrolase. | Threonine synthase. | 0.964 |
| CEL28506.1 | trpB | SRM1_01845 | SRM1_00162 | Haloacid dehalogenase-like hydrolase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.962 |
| cysE_1 | CEL28506.1 | SRM1_00301 | SRM1_01845 | Serine acetyltransferase. | Haloacid dehalogenase-like hydrolase. | 0.957 |
| cysE_1 | cysE_2 | SRM1_00301 | SRM1_04658 | Serine acetyltransferase. | Serine acetyltransferase. | 0.961 |
| cysE_1 | glyA2_1 | SRM1_00301 | SRM1_04928 | Serine acetyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| cysE_1 | glyA2_2 | SRM1_00301 | SRM1_05308 | Serine acetyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| cysE_1 | hom | SRM1_00301 | SRM1_01082 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.942 |
| cysE_1 | serB_1 | SRM1_00301 | SRM1_00558 | Serine acetyltransferase. | Phosphoserine phosphatase. | 0.969 |
| cysE_1 | thrB | SRM1_00301 | SRM1_00117 | Serine acetyltransferase. | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. | 0.919 |
| cysE_1 | trpB | SRM1_00301 | SRM1_00162 | Serine acetyltransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
| cysE_2 | CEL28506.1 | SRM1_04658 | SRM1_01845 | Serine acetyltransferase. | Haloacid dehalogenase-like hydrolase. | 0.960 |
| cysE_2 | cysE_1 | SRM1_04658 | SRM1_00301 | Serine acetyltransferase. | Serine acetyltransferase. | 0.961 |