| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | pabB | SRM1_01804 | SRM1_01846 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate synthase component 1. | 0.755 |
| aroC | trpA | SRM1_01804 | SRM1_00163 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.839 |
| aroC | trpB | SRM1_01804 | SRM1_00162 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.704 |
| aroC | trpC | SRM1_01804 | SRM1_05216 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.620 |
| aroC | trpD_1 | SRM1_01804 | SRM1_03421 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase. | 0.502 |
| aroC | trpD_2 | SRM1_01804 | SRM1_05217 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.654 |
| aroC | trpF | SRM1_01804 | SRM1_01992 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.515 |
| aroC | trpG | SRM1_01804 | SRM1_05218 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component 2. | 0.746 |
| folK_2 | pabB | SRM1_05246 | SRM1_01846 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Aminodeoxychorismate synthase component 1. | 0.705 |
| folK_2 | trpG | SRM1_05246 | SRM1_05218 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Anthranilate synthase component 2. | 0.453 |
| lgrD | pabB | SRM1_00182 | SRM1_01846 | Linear gramicidin synthase subunit D. | Aminodeoxychorismate synthase component 1. | 0.695 |
| pabB | aroC | SRM1_01846 | SRM1_01804 | Aminodeoxychorismate synthase component 1. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.755 |
| pabB | folK_2 | SRM1_01846 | SRM1_05246 | Aminodeoxychorismate synthase component 1. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | 0.705 |
| pabB | lgrD | SRM1_01846 | SRM1_00182 | Aminodeoxychorismate synthase component 1. | Linear gramicidin synthase subunit D. | 0.695 |
| pabB | trpA | SRM1_01846 | SRM1_00163 | Aminodeoxychorismate synthase component 1. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.938 |
| pabB | trpB | SRM1_01846 | SRM1_00162 | Aminodeoxychorismate synthase component 1. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.948 |
| pabB | trpC | SRM1_01846 | SRM1_05216 | Aminodeoxychorismate synthase component 1. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.990 |
| pabB | trpD_1 | SRM1_01846 | SRM1_03421 | Aminodeoxychorismate synthase component 1. | Anthranilate phosphoribosyltransferase. | 0.934 |
| pabB | trpD_2 | SRM1_01846 | SRM1_05217 | Aminodeoxychorismate synthase component 1. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.985 |
| pabB | trpF | SRM1_01846 | SRM1_01992 | Aminodeoxychorismate synthase component 1. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.942 |