| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobH | cysNC | SRM1_00665 | SRM1_00926 | Precorrin-8X methylmutase; Unknown EC_number=5.4.99.61. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.984 |
| cobH | sumT_1 | SRM1_00665 | SRM1_01867 | Precorrin-8X methylmutase; Unknown EC_number=5.4.99.61. | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.761 |
| cysNC | cobH | SRM1_00926 | SRM1_00665 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Precorrin-8X methylmutase; Unknown EC_number=5.4.99.61. | 0.984 |
| cysNC | hemA | SRM1_00926 | SRM1_04800 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.434 |
| cysNC | hemC | SRM1_00926 | SRM1_05626 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.466 |
| cysNC | sumT_1 | SRM1_00926 | SRM1_01867 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.763 |
| hemA | cysNC | SRM1_04800 | SRM1_00926 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.434 |
| hemA | hemB_1 | SRM1_04800 | SRM1_03680 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.854 |
| hemA | hemB_2 | SRM1_04800 | SRM1_05606 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.854 |
| hemA | hemC | SRM1_04800 | SRM1_05626 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.994 |
| hemA | hemL | SRM1_04800 | SRM1_05022 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.956 |
| hemA | sumT_1 | SRM1_04800 | SRM1_01867 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.817 |
| hemB_1 | hemA | SRM1_03680 | SRM1_04800 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.854 |
| hemB_1 | hemC | SRM1_03680 | SRM1_05626 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.970 |
| hemB_1 | hemL | SRM1_03680 | SRM1_05022 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.944 |
| hemB_1 | sumT_1 | SRM1_03680 | SRM1_01867 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.864 |
| hemB_2 | hemA | SRM1_05606 | SRM1_04800 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.854 |
| hemB_2 | hemC | SRM1_05606 | SRM1_05626 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.970 |
| hemB_2 | hemL | SRM1_05606 | SRM1_05022 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.944 |
| hemB_2 | sumT_1 | SRM1_05606 | SRM1_01867 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.859 |