| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acrB | macA_2 | SRM1_04429 | SRM1_01946 | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Macrolide export protein MacA. | 0.616 |
| acrB | ttgC_1 | SRM1_04429 | SRM1_01293 | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Putative efflux pump outer membrane protein TtgC precursor. | 0.835 |
| acrB | ttgF_1 | SRM1_04429 | SRM1_01944 | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Toluene efflux pump outer membrane protein TtgF precursor. | 0.574 |
| acrB | ttgI | SRM1_04429 | SRM1_02794 | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Toluene efflux pump outer membrane protein TtgI precursor. | 0.547 |
| bepE | macA_2 | SRM1_02793 | SRM1_01946 | Efflux pump membrane transporter BepE. | Macrolide export protein MacA. | 0.679 |
| bepE | macB | SRM1_02793 | SRM1_01945 | Efflux pump membrane transporter BepE. | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.460 |
| bepE | ttgC_1 | SRM1_02793 | SRM1_01293 | Efflux pump membrane transporter BepE. | Putative efflux pump outer membrane protein TtgC precursor. | 0.965 |
| bepE | ttgF_1 | SRM1_02793 | SRM1_01944 | Efflux pump membrane transporter BepE. | Toluene efflux pump outer membrane protein TtgF precursor. | 0.857 |
| bepE | ttgI | SRM1_02793 | SRM1_02794 | Efflux pump membrane transporter BepE. | Toluene efflux pump outer membrane protein TtgI precursor. | 0.982 |
| fecI_4 | macA_2 | SRM1_01947 | SRM1_01946 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. | Macrolide export protein MacA. | 0.569 |
| fecI_4 | macB | SRM1_01947 | SRM1_01945 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.556 |
| fecI_4 | pvdA | SRM1_01947 | SRM1_01948 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. | L-ornithine 5-monooxygenase. | 0.626 |
| fecI_4 | ttgF_1 | SRM1_01947 | SRM1_01944 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. | Toluene efflux pump outer membrane protein TtgF precursor. | 0.534 |
| macA_2 | acrB | SRM1_01946 | SRM1_04429 | Macrolide export protein MacA. | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.616 |
| macA_2 | bepE | SRM1_01946 | SRM1_02793 | Macrolide export protein MacA. | Efflux pump membrane transporter BepE. | 0.679 |
| macA_2 | fecI_4 | SRM1_01946 | SRM1_01947 | Macrolide export protein MacA. | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. | 0.569 |
| macA_2 | macB | SRM1_01946 | SRM1_01945 | Macrolide export protein MacA. | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.997 |
| macA_2 | mexB | SRM1_01946 | SRM1_02837 | Macrolide export protein MacA. | Multidrug resistance protein MexB. | 0.700 |
| macA_2 | pvdA | SRM1_01946 | SRM1_01948 | Macrolide export protein MacA. | L-ornithine 5-monooxygenase. | 0.585 |
| macA_2 | ttgB | SRM1_01946 | SRM1_01295 | Macrolide export protein MacA. | Putative efflux pump membrane transporter TtgB. | 0.682 |