| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA_1 | carB_1 | SRM1_00812 | SRM1_00813 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
| carA_1 | preA | SRM1_00812 | SRM1_03227 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | 0.809 |
| carA_1 | purL | SRM1_00812 | SRM1_01044 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.988 |
| carA_1 | pyrB | SRM1_00812 | SRM1_05407 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA_1 | pyrE | SRM1_00812 | SRM1_05683 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.909 |
| carA_1 | pyrF | SRM1_00812 | SRM1_04143 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.915 |
| carA_1 | pyrR | SRM1_00812 | SRM1_05406 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Bifunctional protein PyrR. | 0.824 |
| carA_1 | uacT_2 | SRM1_00812 | SRM1_01963 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Uric acid transporter UacT. | 0.565 |
| carB_1 | carA_1 | SRM1_00813 | SRM1_00812 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
| carB_1 | preA | SRM1_00813 | SRM1_03227 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | 0.841 |
| carB_1 | purL | SRM1_00813 | SRM1_01044 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.751 |
| carB_1 | pyrB | SRM1_00813 | SRM1_05407 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB_1 | pyrE | SRM1_00813 | SRM1_05683 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.940 |
| carB_1 | pyrF | SRM1_00813 | SRM1_04143 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.944 |
| carB_1 | pyrR | SRM1_00813 | SRM1_05406 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Bifunctional protein PyrR. | 0.884 |
| carB_1 | uacT_2 | SRM1_00813 | SRM1_01963 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Uric acid transporter UacT. | 0.490 |
| preA | carA_1 | SRM1_03227 | SRM1_00812 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.809 |
| preA | carB_1 | SRM1_03227 | SRM1_00813 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.841 |
| preA | pucI_2 | SRM1_03227 | SRM1_01843 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Putative allantoin permease. | 0.618 |
| preA | purL | SRM1_03227 | SRM1_01044 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.652 |