node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEL28645.1 | dapA_1 | SRM1_01989 | SRM1_01361 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.794 |
CEL28645.1 | dapA_2 | SRM1_01989 | SRM1_02268 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | 0.705 |
CEL28645.1 | dapB | SRM1_01989 | SRM1_00811 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.619 |
CEL28645.1 | dapF_2 | SRM1_01989 | SRM1_05637 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.622 |
CEL28645.1 | gltB | SRM1_01989 | SRM1_00466 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | Glutamate synthase [NADPH] large chain precursor. | 0.668 |
CEL28645.1 | hom | SRM1_01989 | SRM1_01082 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine dehydrogenase. | 0.942 |
CEL28645.1 | leuB | SRM1_01989 | SRM1_01987 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.676 |
CEL28645.1 | lysC | SRM1_01989 | SRM1_04222 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate; Belongs to the aspartokinase family. | 0.903 |
CEL28645.1 | pgk | SRM1_01989 | SRM1_05356 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.572 |
CEL28645.1 | truA | SRM1_01989 | SRM1_01991 | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.752 |
dapA_1 | CEL28645.1 | SRM1_01361 | SRM1_01989 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.794 |
dapA_1 | dapB | SRM1_01361 | SRM1_00811 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.949 |
dapA_1 | dapF_2 | SRM1_01361 | SRM1_05637 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.763 |
dapA_1 | hom | SRM1_01361 | SRM1_01082 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Homoserine dehydrogenase. | 0.645 |
dapA_1 | lysC | SRM1_01361 | SRM1_04222 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate; Belongs to the aspartokinase family. | 0.707 |
dapA_1 | truA | SRM1_01361 | SRM1_01991 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.413 |
dapA_2 | CEL28645.1 | SRM1_02268 | SRM1_01989 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | USG-1 protein homolog; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.705 |
dapA_2 | dapB | SRM1_02268 | SRM1_00811 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.785 |
dapA_2 | hom | SRM1_02268 | SRM1_01082 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Homoserine dehydrogenase. | 0.441 |
dapA_2 | lysC | SRM1_02268 | SRM1_04222 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate; Belongs to the aspartokinase family. | 0.444 |