| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB_1 | purC | SRM1_00813 | SRM1_01364 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.485 |
| carB_1 | purD | SRM1_00813 | SRM1_00679 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.759 |
| carB_1 | purE | SRM1_00813 | SRM1_05770 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.697 |
| carB_1 | purF | SRM1_00813 | SRM1_01997 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.995 |
| carB_1 | purH | SRM1_00813 | SRM1_00680 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Bifunctional purine biosynthesis protein PurH. | 0.836 |
| carB_1 | purK | SRM1_00813 | SRM1_05769 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.567 |
| carB_1 | purL | SRM1_00813 | SRM1_01044 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.931 |
| carB_1 | purM | SRM1_00813 | SRM1_01630 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.729 |
| carB_1 | purN | SRM1_00813 | SRM1_01629 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.651 |
| cvpA | purC | SRM1_01996 | SRM1_01364 | Colicin V production protein. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.921 |
| cvpA | purD | SRM1_01996 | SRM1_00679 | Colicin V production protein. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.504 |
| cvpA | purE | SRM1_01996 | SRM1_05770 | Colicin V production protein. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.770 |
| cvpA | purF | SRM1_01996 | SRM1_01997 | Colicin V production protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.993 |
| cvpA | purH | SRM1_01996 | SRM1_00680 | Colicin V production protein. | Bifunctional purine biosynthesis protein PurH. | 0.664 |
| cvpA | purK | SRM1_01996 | SRM1_05769 | Colicin V production protein. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.583 |
| cvpA | purL | SRM1_01996 | SRM1_01044 | Colicin V production protein. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.968 |
| cvpA | purM | SRM1_01996 | SRM1_01630 | Colicin V production protein. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.927 |
| cvpA | purN | SRM1_01996 | SRM1_01629 | Colicin V production protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.688 |
| purC | carB_1 | SRM1_01364 | SRM1_00813 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.485 |
| purC | cvpA | SRM1_01364 | SRM1_01996 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Colicin V production protein. | 0.921 |