| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL29141.1 | xanP_2 | SRM1_02490 | SRM1_02491 | Late embryogenesis abundant protein. | Xanthine permease XanP. | 0.585 |
| carB_1 | preA | SRM1_00813 | SRM1_03227 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | 0.888 |
| carB_1 | purL | SRM1_00813 | SRM1_01044 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.931 |
| carB_1 | pyrB | SRM1_00813 | SRM1_05407 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB_1 | pyrD | SRM1_00813 | SRM1_01875 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.963 |
| carB_1 | pyrE | SRM1_00813 | SRM1_05683 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.964 |
| carB_1 | pyrF | SRM1_00813 | SRM1_04143 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.965 |
| carB_1 | pyrR | SRM1_00813 | SRM1_05406 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Bifunctional protein PyrR. | 0.857 |
| carB_1 | xanP_2 | SRM1_00813 | SRM1_02491 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Xanthine permease XanP. | 0.490 |
| preA | carB_1 | SRM1_03227 | SRM1_00813 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.888 |
| preA | purL | SRM1_03227 | SRM1_01044 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.675 |
| preA | pyrB | SRM1_03227 | SRM1_05407 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.849 |
| preA | pyrE | SRM1_03227 | SRM1_05683 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.897 |
| preA | pyrF | SRM1_03227 | SRM1_04143 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.876 |
| preA | pyrR | SRM1_03227 | SRM1_05406 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Bifunctional protein PyrR. | 0.978 |
| preA | xanP_2 | SRM1_03227 | SRM1_02491 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Xanthine permease XanP. | 0.466 |
| purL | carB_1 | SRM1_01044 | SRM1_00813 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.931 |
| purL | preA | SRM1_01044 | SRM1_03227 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | 0.675 |
| purL | pyrB | SRM1_01044 | SRM1_05407 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.767 |
| purL | pyrD | SRM1_01044 | SRM1_01875 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.677 |