Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
aprFOuter membrane protein precursor. (451 aa)    
Predicted Functional Partners:
aprE
Type I secretion system membrane fusion protein.
 
 0.972
aprD
Type I secretion system ATP-binding protein.
 
  
 0.961
mdtA_1
Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.883
mdtA_2
Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.882
ttgA
Putative efflux pump periplasmic linker TtgA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.834
acrE
Multidrug export protein AcrE precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.834
emrK_1
Putative multidrug resistance protein EmrK.
  
 0.807
emrA
Multidrug export protein EmrA.
  
 0.807
macB
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.805
ttgB
Putative efflux pump membrane transporter TtgB.
  
 0.774
Your Current Organism:
Pseudomonas fluorescens
NCBI taxonomy Id: 294
Other names: ATCC 13525, Bacillus fluorescens, Bacillus fluorescens liquefaciens, Bacterium fluorescen, CCEB 546, CFBP 2102, CIP 69.13, DSM 50090, IAM 12022, IFO 14160, JCM 5963, Liquidomonas fluorescens, NBRC 14160, NCCB 76040, NCIB 9046, NCIB:9046, NCIMB 9046, NCTC 10038, NRRL B-14678, P. fluorescens, Pseudomonas sp. AU2390, Pseudomonas sp. BZ64, Pseudomonas sp. FY32, Pseudomonas sp. HSA2/2016, Pseudomonas sp. HSA3/2016, Pseudomonas sp. ISSDS-433, Pseudomonas sp. JCM 17186, Pseudomonas sp. JCM 2779, Pseudomonas sp. KH-20150KS3, Pseudomonas sp. LBUM223, Pseudomonas sp. LBUM636, Pseudomonas sp. SM2/2016, RH 818, VKM B-894, bacterium P1-1, strain M. Rhodes 28/5
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