| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaA | ftsI | SRM1_00056 | SRM1_04727 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.440 |
| dnaA | ftsK | SRM1_00056 | SRM1_03428 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA translocase FtsK. | 0.736 |
| dnaA | ftsW | SRM1_00056 | SRM1_04722 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.522 |
| dnaA | mraZ | SRM1_00056 | SRM1_04730 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Protein MraZ; Belongs to the MraZ family. | 0.490 |
| dnaA | parA | SRM1_00056 | SRM1_00050 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Chromosome partitioning protein ParA. | 0.713 |
| dnaA | parB | SRM1_00056 | SRM1_00049 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Putative chromosome-partitioning protein ParB; Belongs to the ParB family. | 0.744 |
| dnaA | ruvB | SRM1_00056 | SRM1_04344 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.549 |
| ftsI | dnaA | SRM1_04727 | SRM1_00056 | Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.440 |
| ftsI | ftsK | SRM1_04727 | SRM1_03428 | Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | DNA translocase FtsK. | 0.766 |
| ftsI | ftsQ | SRM1_04727 | SRM1_04718 | Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.935 |
| ftsI | ftsW | SRM1_04727 | SRM1_04722 | Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.980 |
| ftsI | mraZ | SRM1_04727 | SRM1_04730 | Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Protein MraZ; Belongs to the MraZ family. | 0.928 |
| ftsK | dnaA | SRM1_03428 | SRM1_00056 | DNA translocase FtsK. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.736 |
| ftsK | ftsI | SRM1_03428 | SRM1_04727 | DNA translocase FtsK. | Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.766 |
| ftsK | ftsQ | SRM1_03428 | SRM1_04718 | DNA translocase FtsK. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.871 |
| ftsK | ftsW | SRM1_03428 | SRM1_04722 | DNA translocase FtsK. | Lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.737 |
| ftsK | lolA_2 | SRM1_03428 | SRM1_03427 | DNA translocase FtsK. | Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.807 |
| ftsK | mraZ | SRM1_03428 | SRM1_04730 | DNA translocase FtsK. | Protein MraZ; Belongs to the MraZ family. | 0.737 |
| ftsK | parA | SRM1_03428 | SRM1_00050 | DNA translocase FtsK. | Chromosome partitioning protein ParA. | 0.723 |
| ftsK | parB | SRM1_03428 | SRM1_00049 | DNA translocase FtsK. | Putative chromosome-partitioning protein ParB; Belongs to the ParB family. | 0.879 |