| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| metH | rfbD | SRM1_02950 | SRM1_04014 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | dTDP-4-dehydrorhamnose reductase. | 0.721 |
| metH | rmlD | SRM1_02950 | SRM1_05126 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.721 |
| rfbB | rfbC_1 | SRM1_04015 | SRM1_00339 | dTDP-glucose 4,6-dehydratase. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.999 |
| rfbB | rfbC_2 | SRM1_04015 | SRM1_01501 | dTDP-glucose 4,6-dehydratase. | dTDP-4-dehydrorhamnose 3,5-epimerase. | 0.984 |
| rfbB | rfbD | SRM1_04015 | SRM1_04014 | dTDP-glucose 4,6-dehydratase. | dTDP-4-dehydrorhamnose reductase. | 0.999 |
| rfbB | rfbG | SRM1_04015 | SRM1_01500 | dTDP-glucose 4,6-dehydratase. | CDP-glucose 4,6-dehydratase. | 0.423 |
| rfbB | rmlA2 | SRM1_04015 | SRM1_04013 | dTDP-glucose 4,6-dehydratase. | Glucose-1-phosphate thymidylyltransferase 2. | 0.999 |
| rfbB | rmlD | SRM1_04015 | SRM1_05126 | dTDP-glucose 4,6-dehydratase. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.994 |
| rfbB | tll | SRM1_04015 | SRM1_01503 | dTDP-glucose 4,6-dehydratase. | dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD(+)). | 0.423 |
| rfbB | wbbL | SRM1_04015 | SRM1_01505 | dTDP-glucose 4,6-dehydratase. | N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase. | 0.699 |
| rfbB | wcaJ_1 | SRM1_04015 | SRM1_03338 | dTDP-glucose 4,6-dehydratase. | UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase. | 0.676 |
| rfbC_1 | rfbB | SRM1_00339 | SRM1_04015 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | dTDP-glucose 4,6-dehydratase. | 0.999 |
| rfbC_1 | rfbC_2 | SRM1_00339 | SRM1_01501 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | dTDP-4-dehydrorhamnose 3,5-epimerase. | 0.696 |
| rfbC_1 | rfbD | SRM1_00339 | SRM1_04014 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | dTDP-4-dehydrorhamnose reductase. | 0.999 |
| rfbC_1 | rfbG | SRM1_00339 | SRM1_01500 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | CDP-glucose 4,6-dehydratase. | 0.772 |
| rfbC_1 | rmlA2 | SRM1_00339 | SRM1_04013 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | Glucose-1-phosphate thymidylyltransferase 2. | 0.993 |
| rfbC_1 | rmlD | SRM1_00339 | SRM1_05126 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.993 |
| rfbC_1 | tll | SRM1_00339 | SRM1_01503 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD(+)). | 0.424 |
| rfbC_1 | wbbL | SRM1_00339 | SRM1_01505 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase. | 0.774 |
| rfbC_1 | wcaJ_1 | SRM1_00339 | SRM1_03338 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase. | 0.663 |