| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adk | cmk_2 | SRM1_04522 | SRM1_04020 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Cytidylate kinase. | 0.623 |
| adk | cpdA | SRM1_04522 | SRM1_00550 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.955 |
| adk | mazG | SRM1_04522 | SRM1_04162 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Nucleoside triphosphate pyrophosphohydrolase. | 0.965 |
| adk | pyrG | SRM1_04522 | SRM1_01147 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.605 |
| adk | tmk_3 | SRM1_04522 | SRM1_04100 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.581 |
| cmk_2 | adk | SRM1_04020 | SRM1_04522 | Cytidylate kinase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.623 |
| cmk_2 | mazG | SRM1_04020 | SRM1_04162 | Cytidylate kinase. | Nucleoside triphosphate pyrophosphohydrolase. | 0.965 |
| cmk_2 | pyrG | SRM1_04020 | SRM1_01147 | Cytidylate kinase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.500 |
| cmk_2 | yhdE | SRM1_04020 | SRM1_00888 | Cytidylate kinase. | Maf-like protein YhdE. | 0.958 |
| cpdA | adk | SRM1_00550 | SRM1_04522 | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.955 |
| cpdA | mazG | SRM1_00550 | SRM1_04162 | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Nucleoside triphosphate pyrophosphohydrolase. | 0.963 |
| mazG | adk | SRM1_04162 | SRM1_04522 | Nucleoside triphosphate pyrophosphohydrolase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.965 |
| mazG | cmk_2 | SRM1_04162 | SRM1_04020 | Nucleoside triphosphate pyrophosphohydrolase. | Cytidylate kinase. | 0.965 |
| mazG | cpdA | SRM1_04162 | SRM1_00550 | Nucleoside triphosphate pyrophosphohydrolase. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.963 |
| mazG | pncB2 | SRM1_04162 | SRM1_00613 | Nucleoside triphosphate pyrophosphohydrolase. | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.962 |
| mazG | pyrG | SRM1_04162 | SRM1_01147 | Nucleoside triphosphate pyrophosphohydrolase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.965 |
| mazG | relA_2 | SRM1_04162 | SRM1_04163 | Nucleoside triphosphate pyrophosphohydrolase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.994 |
| mazG | spoT | SRM1_04162 | SRM1_05691 | Nucleoside triphosphate pyrophosphohydrolase. | Bifunctional (p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.965 |
| mazG | sthA | SRM1_04162 | SRM1_03773 | Nucleoside triphosphate pyrophosphohydrolase. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.967 |
| mazG | tmk_3 | SRM1_04162 | SRM1_04100 | Nucleoside triphosphate pyrophosphohydrolase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.960 |