| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alaS_2 | ltaE_1 | SRM1_04223 | SRM1_04224 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Low specificity L-threonine aldolase. | 0.561 |
| alaS_2 | lysC | SRM1_04223 | SRM1_04222 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate; Belongs to the aspartokinase family. | 0.774 |
| alaS_2 | ychF | SRM1_04223 | SRM1_04808 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.507 |
| gcvP_1 | gcvP_2 | SRM1_04328 | SRM1_05571 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine dehydrogenase (decarboxylating). | 0.999 |
| gcvP_1 | gltB | SRM1_04328 | SRM1_00466 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glutamate synthase [NADPH] large chain precursor. | 0.732 |
| gcvP_1 | ltaE_1 | SRM1_04328 | SRM1_04224 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Low specificity L-threonine aldolase. | 0.540 |
| gcvP_2 | gcvP_1 | SRM1_05571 | SRM1_04328 | Glycine dehydrogenase (decarboxylating). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcvP_2 | gltB | SRM1_05571 | SRM1_00466 | Glycine dehydrogenase (decarboxylating). | Glutamate synthase [NADPH] large chain precursor. | 0.732 |
| gcvP_2 | ltaE_1 | SRM1_05571 | SRM1_04224 | Glycine dehydrogenase (decarboxylating). | Low specificity L-threonine aldolase. | 0.540 |
| gltB | gcvP_1 | SRM1_00466 | SRM1_04328 | Glutamate synthase [NADPH] large chain precursor. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.732 |
| gltB | gcvP_2 | SRM1_00466 | SRM1_05571 | Glutamate synthase [NADPH] large chain precursor. | Glycine dehydrogenase (decarboxylating). | 0.732 |
| gltB | ltaE_1 | SRM1_00466 | SRM1_04224 | Glutamate synthase [NADPH] large chain precursor. | Low specificity L-threonine aldolase. | 0.537 |
| gltB | lysC | SRM1_00466 | SRM1_04222 | Glutamate synthase [NADPH] large chain precursor. | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate; Belongs to the aspartokinase family. | 0.627 |
| ltaE_1 | alaS_2 | SRM1_04224 | SRM1_04223 | Low specificity L-threonine aldolase. | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.561 |
| ltaE_1 | gcvP_1 | SRM1_04224 | SRM1_04328 | Low specificity L-threonine aldolase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.540 |
| ltaE_1 | gcvP_2 | SRM1_04224 | SRM1_05571 | Low specificity L-threonine aldolase. | Glycine dehydrogenase (decarboxylating). | 0.540 |
| ltaE_1 | gltB | SRM1_04224 | SRM1_00466 | Low specificity L-threonine aldolase. | Glutamate synthase [NADPH] large chain precursor. | 0.537 |
| ltaE_1 | lysC | SRM1_04224 | SRM1_04222 | Low specificity L-threonine aldolase. | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate; Belongs to the aspartokinase family. | 0.518 |
| ltaE_1 | ychF | SRM1_04224 | SRM1_04808 | Low specificity L-threonine aldolase. | Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.864 |
| lysC | alaS_2 | SRM1_04222 | SRM1_04223 | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate; Belongs to the aspartokinase family. | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.774 |