| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysG | cysNC | SRM1_03423 | SRM1_00926 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.967 |
| cysG | gltB | SRM1_03423 | SRM1_00466 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Glutamate synthase [NADPH] large chain precursor. | 0.779 |
| cysG | pitA_2 | SRM1_03423 | SRM1_04263 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Low-affinity inorganic phosphate transporter 1. | 0.627 |
| cysNC | cysG | SRM1_00926 | SRM1_03423 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.967 |
| cysNC | gltB | SRM1_00926 | SRM1_00466 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Glutamate synthase [NADPH] large chain precursor. | 0.759 |
| cysNC | pitA_2 | SRM1_00926 | SRM1_04263 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Low-affinity inorganic phosphate transporter 1. | 0.470 |
| cysNC | pstA | SRM1_00926 | SRM1_05761 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Phosphate transport system permease protein PstA. | 0.429 |
| cysNC | pstB | SRM1_00926 | SRM1_05760 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Phosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.410 |
| gltB | cysG | SRM1_00466 | SRM1_03423 | Glutamate synthase [NADPH] large chain precursor. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.779 |
| gltB | cysNC | SRM1_00466 | SRM1_00926 | Glutamate synthase [NADPH] large chain precursor. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.759 |
| gltB | pitA_2 | SRM1_00466 | SRM1_04263 | Glutamate synthase [NADPH] large chain precursor. | Low-affinity inorganic phosphate transporter 1. | 0.439 |
| gltB | pstB | SRM1_00466 | SRM1_05760 | Glutamate synthase [NADPH] large chain precursor. | Phosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.512 |
| phoR_2 | pitA_2 | SRM1_05755 | SRM1_04263 | Phosphate regulon sensor protein PhoR. | Low-affinity inorganic phosphate transporter 1. | 0.427 |
| phoR_2 | pstA | SRM1_05755 | SRM1_05761 | Phosphate regulon sensor protein PhoR. | Phosphate transport system permease protein PstA. | 0.725 |
| phoR_2 | pstB | SRM1_05755 | SRM1_05760 | Phosphate regulon sensor protein PhoR. | Phosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.650 |
| pitA_2 | cysG | SRM1_04263 | SRM1_03423 | Low-affinity inorganic phosphate transporter 1. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.627 |
| pitA_2 | cysNC | SRM1_04263 | SRM1_00926 | Low-affinity inorganic phosphate transporter 1. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.470 |
| pitA_2 | gltB | SRM1_04263 | SRM1_00466 | Low-affinity inorganic phosphate transporter 1. | Glutamate synthase [NADPH] large chain precursor. | 0.439 |
| pitA_2 | phoR_2 | SRM1_04263 | SRM1_05755 | Low-affinity inorganic phosphate transporter 1. | Phosphate regulon sensor protein PhoR. | 0.427 |
| pitA_2 | pstA | SRM1_04263 | SRM1_05761 | Low-affinity inorganic phosphate transporter 1. | Phosphate transport system permease protein PstA. | 0.722 |