| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| eda | edd | SRM1_04297 | SRM1_04311 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.999 |
| eda | fda | SRM1_04297 | SRM1_05353 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.962 |
| eda | glk | SRM1_04297 | SRM1_04310 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Glucokinase; Belongs to the bacterial glucokinase family. | 0.996 |
| eda | ompR_7 | SRM1_04297 | SRM1_04309 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Transcriptional regulatory protein OmpR. | 0.695 |
| eda | pgi | SRM1_04297 | SRM1_04859 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.973 |
| eda | pgm | SRM1_04297 | SRM1_02772 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Phosphoglucomutase. | 0.959 |
| eda | tal | SRM1_04297 | SRM1_03757 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.482 |
| eda | zwf_1 | SRM1_04297 | SRM1_02500 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.766 |
| eda | zwf_2 | SRM1_04297 | SRM1_04299 | 2-dehydro-3-deoxy-phosphogluconate aldolase. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.972 |
| edd | eda | SRM1_04311 | SRM1_04297 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 2-dehydro-3-deoxy-phosphogluconate aldolase. | 0.999 |
| edd | glk | SRM1_04311 | SRM1_04310 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucokinase; Belongs to the bacterial glucokinase family. | 0.986 |
| edd | ompR_7 | SRM1_04311 | SRM1_04309 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Transcriptional regulatory protein OmpR. | 0.932 |
| edd | pgi | SRM1_04311 | SRM1_04859 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.663 |
| edd | tktA | SRM1_04311 | SRM1_05358 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.494 |
| edd | zwf_1 | SRM1_04311 | SRM1_02500 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.886 |
| edd | zwf_2 | SRM1_04311 | SRM1_04299 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.899 |
| fda | eda | SRM1_05353 | SRM1_04297 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 2-dehydro-3-deoxy-phosphogluconate aldolase. | 0.962 |
| fda | glk | SRM1_05353 | SRM1_04310 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Glucokinase; Belongs to the bacterial glucokinase family. | 0.977 |
| fda | pgi | SRM1_05353 | SRM1_04859 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.995 |
| fda | pgm | SRM1_05353 | SRM1_02772 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Phosphoglucomutase. | 0.962 |