| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fumA | gcvP_1 | SRM1_04395 | SRM1_04328 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.968 |
| fumA | gcvP_2 | SRM1_04395 | SRM1_05571 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine dehydrogenase (decarboxylating). | 0.968 |
| fumA | sdaB_1 | SRM1_04395 | SRM1_04329 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | L-serine dehydratase 2; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.468 |
| gcvH_1 | gcvP_1 | SRM1_04327 | SRM1_04328 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcvH_1 | gcvP_2 | SRM1_04327 | SRM1_05571 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating). | 0.999 |
| gcvH_1 | gcvT_1 | SRM1_04327 | SRM1_04330 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase. | 0.995 |
| gcvH_1 | gcvT_2 | SRM1_04327 | SRM1_05305 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; Belongs to the GcvT family. | 0.962 |
| gcvH_1 | putA | SRM1_04327 | SRM1_00506 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.413 |
| gcvH_1 | sdaB_1 | SRM1_04327 | SRM1_04329 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | L-serine dehydratase 2; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.645 |
| gcvP_1 | fumA | SRM1_04328 | SRM1_04395 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.968 |
| gcvP_1 | gcvH_1 | SRM1_04328 | SRM1_04327 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvP_1 | gcvP_2 | SRM1_04328 | SRM1_05571 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine dehydrogenase (decarboxylating). | 0.999 |
| gcvP_1 | gcvT_1 | SRM1_04328 | SRM1_04330 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Aminomethyltransferase. | 0.998 |
| gcvP_1 | gcvT_2 | SRM1_04328 | SRM1_05305 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Aminomethyltransferase; Belongs to the GcvT family. | 0.991 |
| gcvP_1 | sdaB_1 | SRM1_04328 | SRM1_04329 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | L-serine dehydratase 2; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.804 |
| gcvP_2 | fumA | SRM1_05571 | SRM1_04395 | Glycine dehydrogenase (decarboxylating). | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.968 |
| gcvP_2 | gcvH_1 | SRM1_05571 | SRM1_04327 | Glycine dehydrogenase (decarboxylating). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvP_2 | gcvP_1 | SRM1_05571 | SRM1_04328 | Glycine dehydrogenase (decarboxylating). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcvP_2 | gcvT_1 | SRM1_05571 | SRM1_04330 | Glycine dehydrogenase (decarboxylating). | Aminomethyltransferase. | 0.996 |
| gcvP_2 | gcvT_2 | SRM1_05571 | SRM1_05305 | Glycine dehydrogenase (decarboxylating). | Aminomethyltransferase; Belongs to the GcvT family. | 0.994 |