node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acrB | mdtA_3 | SRM1_04429 | SRM1_04513 | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.715 |
acrB | tolC_1 | SRM1_04429 | SRM1_00543 | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Outer membrane protein TolC precursor. | 0.481 |
bepE | macB | SRM1_02793 | SRM1_01945 | Efflux pump membrane transporter BepE. | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.460 |
bepE | mdtA_3 | SRM1_02793 | SRM1_04513 | Efflux pump membrane transporter BepE. | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.698 |
cnrA | mdtA_3 | SRM1_04512 | SRM1_04513 | Nickel and cobalt resistance protein CnrA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.978 |
cnrA | srpR | SRM1_04512 | SRM1_04514 | Nickel and cobalt resistance protein CnrA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | HTH-type transcriptional regulator SrpR. | 0.678 |
czcA_1 | mdtA_3 | SRM1_00285 | SRM1_04513 | Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.906 |
macB | bepE | SRM1_01945 | SRM1_02793 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Efflux pump membrane transporter BepE. | 0.460 |
macB | mdtA_3 | SRM1_01945 | SRM1_04513 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.912 |
macB | mexB | SRM1_01945 | SRM1_02837 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Multidrug resistance protein MexB. | 0.620 |
macB | tolC_1 | SRM1_01945 | SRM1_00543 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Outer membrane protein TolC precursor. | 0.784 |
macB | ttgB | SRM1_01945 | SRM1_01295 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Putative efflux pump membrane transporter TtgB. | 0.412 |
mdtA_3 | acrB | SRM1_04513 | SRM1_04429 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.715 |
mdtA_3 | bepE | SRM1_04513 | SRM1_02793 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Efflux pump membrane transporter BepE. | 0.698 |
mdtA_3 | cnrA | SRM1_04513 | SRM1_04512 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Nickel and cobalt resistance protein CnrA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.978 |
mdtA_3 | czcA_1 | SRM1_04513 | SRM1_00285 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.906 |
mdtA_3 | macB | SRM1_04513 | SRM1_01945 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.912 |
mdtA_3 | mdtC | SRM1_04513 | SRM1_02437 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug resistance protein MdtC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.628 |
mdtA_3 | mexB | SRM1_04513 | SRM1_02837 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug resistance protein MexB. | 0.697 |
mdtA_3 | srpR | SRM1_04513 | SRM1_04514 | Multidrug resistance protein MdtA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | HTH-type transcriptional regulator SrpR. | 0.746 |