| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hisS | ispG | SRM1_04644 | SRM1_04645 | Histidine--tRNA ligase. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.894 |
| hisS | rlmN | SRM1_04644 | SRM1_04648 | Histidine--tRNA ligase. | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.738 |
| hisS | rodZ | SRM1_04644 | SRM1_04646 | Histidine--tRNA ligase. | Cytoskeleton protein RodZ. | 0.776 |
| hisS | rplV | SRM1_04644 | SRM1_05174 | Histidine--tRNA ligase. | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.442 |
| hisS | rplW | SRM1_04644 | SRM1_05177 | Histidine--tRNA ligase. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.535 |
| hisS | ycf3 | SRM1_04644 | SRM1_04647 | Histidine--tRNA ligase. | Photosystem I assembly protein Ycf3. | 0.715 |
| ispG | hisS | SRM1_04645 | SRM1_04644 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | Histidine--tRNA ligase. | 0.894 |
| ispG | rlmN | SRM1_04645 | SRM1_04648 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.852 |
| ispG | rodZ | SRM1_04645 | SRM1_04646 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | Cytoskeleton protein RodZ. | 0.931 |
| ispG | ycf3 | SRM1_04645 | SRM1_04647 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | Photosystem I assembly protein Ycf3. | 0.805 |
| mreB | mreC | SRM1_00885 | SRM1_00886 | Rod shape-determining protein MreB. | Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.995 |
| mreB | rodZ | SRM1_00885 | SRM1_04646 | Rod shape-determining protein MreB. | Cytoskeleton protein RodZ. | 0.984 |
| mreC | mreB | SRM1_00886 | SRM1_00885 | Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape. | Rod shape-determining protein MreB. | 0.995 |
| mreC | rodZ | SRM1_00886 | SRM1_04646 | Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape. | Cytoskeleton protein RodZ. | 0.761 |
| pgsA | rodZ | SRM1_02904 | SRM1_04646 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Cytoskeleton protein RodZ. | 0.801 |
| pgsA | secA | SRM1_02904 | SRM1_04364 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.478 |
| rlmN | hisS | SRM1_04648 | SRM1_04644 | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Histidine--tRNA ligase. | 0.738 |
| rlmN | ispG | SRM1_04648 | SRM1_04645 | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.852 |
| rlmN | rodZ | SRM1_04648 | SRM1_04646 | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Cytoskeleton protein RodZ. | 0.801 |
| rlmN | ycf3 | SRM1_04648 | SRM1_04647 | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Photosystem I assembly protein Ycf3. | 0.826 |