| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| nadC | nadD | SRM1_00833 | SRM1_05048 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.988 |
| nadC | nadE | SRM1_00833 | SRM1_00612 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.771 |
| nadC | nudC_2 | SRM1_00833 | SRM1_02531 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.955 |
| nadC | pncB2 | SRM1_00833 | SRM1_00613 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.993 |
| nadC | pncC_1 | SRM1_00833 | SRM1_01188 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.967 |
| nadC | pncC_2 | SRM1_00833 | SRM1_02712 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | Nicotinamide-nucleotide amidohydrolase PncC. | 0.961 |
| nadC | rsfS | SRM1_00833 | SRM1_05047 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.434 |
| nadC | surE | SRM1_00833 | SRM1_01157 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.959 |
| nadD | nadC | SRM1_05048 | SRM1_00833 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | 0.988 |
| nadD | nadE | SRM1_05048 | SRM1_00612 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.991 |
| nadD | nudC_2 | SRM1_05048 | SRM1_02531 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.958 |
| nadD | pncB2 | SRM1_05048 | SRM1_00613 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.977 |
| nadD | pncC_1 | SRM1_05048 | SRM1_01188 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.983 |
| nadD | pncC_2 | SRM1_05048 | SRM1_02712 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinamide-nucleotide amidohydrolase PncC. | 0.983 |
| nadD | pntB | SRM1_05048 | SRM1_00170 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.977 |
| nadD | ppnK | SRM1_05048 | SRM1_02239 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.973 |
| nadD | rsfS | SRM1_05048 | SRM1_05047 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.987 |
| nadD | surE | SRM1_05048 | SRM1_01157 | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.961 |
| nadE | nadC | SRM1_00612 | SRM1_00833 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | 0.771 |
| nadE | nadD | SRM1_00612 | SRM1_05048 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.991 |