node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEL31930.1 | antA | SRM1_05304 | SRM1_05313 | Sarcosine oxidase, gamma subunit family. | Anthranilate 1,2-dioxygenase large subunit. | 0.902 |
CEL31930.1 | gcvT_2 | SRM1_05304 | SRM1_05305 | Sarcosine oxidase, gamma subunit family. | Aminomethyltransferase; Belongs to the GcvT family. | 0.999 |
CEL31930.1 | glyA2_2 | SRM1_05304 | SRM1_05308 | Sarcosine oxidase, gamma subunit family. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.504 |
CEL31930.1 | hcr_1 | SRM1_05304 | SRM1_05312 | Sarcosine oxidase, gamma subunit family. | NADH oxidoreductase hcr. | 0.817 |
CEL31930.1 | soxB | SRM1_05304 | SRM1_05307 | Sarcosine oxidase, gamma subunit family. | Sarcosine oxidase subunit beta. | 0.929 |
CEL31930.1 | soxD | SRM1_05304 | SRM1_05306 | Sarcosine oxidase, gamma subunit family. | Sarcosine oxidase, delta subunit family. | 0.994 |
antA | CEL31930.1 | SRM1_05313 | SRM1_05304 | Anthranilate 1,2-dioxygenase large subunit. | Sarcosine oxidase, gamma subunit family. | 0.902 |
antA | gcvT_2 | SRM1_05313 | SRM1_05305 | Anthranilate 1,2-dioxygenase large subunit. | Aminomethyltransferase; Belongs to the GcvT family. | 0.888 |
antA | hcr_1 | SRM1_05313 | SRM1_05312 | Anthranilate 1,2-dioxygenase large subunit. | NADH oxidoreductase hcr. | 0.973 |
antA | soxB | SRM1_05313 | SRM1_05307 | Anthranilate 1,2-dioxygenase large subunit. | Sarcosine oxidase subunit beta. | 0.748 |
antA | soxD | SRM1_05313 | SRM1_05306 | Anthranilate 1,2-dioxygenase large subunit. | Sarcosine oxidase, delta subunit family. | 0.914 |
gcvH_1 | gcvP_1 | SRM1_04327 | SRM1_04328 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH_1 | gcvP_2 | SRM1_04327 | SRM1_05571 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating). | 0.999 |
gcvH_1 | gcvT_2 | SRM1_04327 | SRM1_05305 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; Belongs to the GcvT family. | 0.962 |
gcvH_1 | glyA2_2 | SRM1_04327 | SRM1_05308 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.617 |
gcvH_2 | gcvP_1 | SRM1_05572 | SRM1_04328 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH_2 | gcvP_2 | SRM1_05572 | SRM1_05571 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating). | 0.999 |
gcvH_2 | gcvT_2 | SRM1_05572 | SRM1_05305 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; Belongs to the GcvT family. | 0.981 |
gcvH_2 | glyA2_2 | SRM1_05572 | SRM1_05308 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.625 |
gcvP_1 | gcvH_1 | SRM1_04328 | SRM1_04327 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |