STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydfG_1NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (257 aa)    
Predicted Functional Partners:
Lbru_1743
Polyketide synthase.
 
 0.933
Lbru_1493
Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.848
Lbru_1742
HAD-superfamily phosphatase.
  
 
 0.764
Lbru_2388
Polyketide synthase module.
  
 
 0.745
Lbru_1401
Polyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.731
gcsB
Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
 
      0.700
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.590
gcvPA
Putative glycine dehydrogenase [decarboxylating] subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
 
      0.573
ltaE
Low specificity L-threonine aldolase.
    
  0.572
Lbru_1462
Polyketide synthase.
  
 
 0.561
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
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