Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
Lbru_1963Hypothetical protein. (500 aa)    
Predicted Functional Partners:
iraA
Small-molecule methyltransferase IraA.
     
 0.792
Lbru_1404
Amino acid permease.
  
     0.577
Lbru_3205
Zip family transporter.
  
 
 
 0.558
Lbru_1277
Cysteine protease.
  
     0.507
lly
4-hydroxyphenylpyruvate dioxygenase.
     
 0.445
Lbru_2150
Amino acid antiporter.
  
 
   0.439
proA_2
Zinc metalloproteinase precursor; Extracellular zinc metalloprotease.
  
   
 0.426
gadC
Glutamate/gamma-aminobutyrate antiporter.
  
 
   0.411
Lbru_0611
Sodium:dicarboxylate symporter protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
 
 0.409
Lbru_2393
Amino acid permease.
  
 
   0.401
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
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