Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acsAacetyl-CoA synthetase. (646 aa)    
Predicted Functional Partners:
mvaB
hydroxymethylglutaryl-CoA lyase.
 
 
 0.928
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.921
yfcX
Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.906
Lbru_0616
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.870
Lbru_2171
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.870
Lbru_1742
HAD-superfamily phosphatase.
  
 0.849
Lbru_2166
3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.836
adc
Acetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family.
     
  0.836
phaB2
Acetyoacetyl CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.836
Lbru_2906
Acetyoacetyl CoA reductase.
     
  0.836
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.