STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbru_2011Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (358 aa)    
Predicted Functional Partners:
Lbru_2854
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
 
 
 0.971
Lbru_1041
Glutamate synthase; Belongs to the glutamate synthase family.
  
 0.969
fadH
2,4-dienoyl-CoA reductase FadH1.
  
 0.847
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.825
Lbru_0540
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.820
icd
Isocitrate dehydrogenase.
   
 0.809
lly
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.792
pdhA
Pyruvate dehydrogenase e1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.786
Lbru_1742
HAD-superfamily phosphatase.
  
 
 0.784
Lbru_0822
Hydrolase.
  
 
 0.740
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.