Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lbru_2012SAM-dependent O-methyltransferase. (220 aa)    
Predicted Functional Partners:
Lbru_1742
HAD-superfamily phosphatase.
    
 0.819
lly
4-hydroxyphenylpyruvate dioxygenase.
  
  
 0.814
phaB_6
Acetyoacetyl CoA reductase.
 
  
   0.805
phaB_2
Acetyoacetyl CoA reductase.
 
  
   0.789
Lbru_2011
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
       0.768
fabG_2
3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
   0.763
phaB_3
Acetyoacetyl CoA reductase.
 
  
   0.718
phaB_4
Acetoacetyl CoA reductase.
 
  
   0.706
phaB2
Acetyoacetyl CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
   0.704
Lbru_2014
Fumarylacetoacetate hydrolase.
     
 0.676
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
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