Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Lbru_2425CBS domain protein. (187 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.743
copA1_2
Copper efflux ATPase.
   
   0.577
Lbru_2932
Signal transduction protein.
  
     0.543
Lbru_2430
Chemiosmotic efflux system protein A-like protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.536
csoR
Copper-sensing transcriptional repressor CsoR.
       0.534
cecC_2
Chemiosmotic efflux system C protein C.
       0.505
ceaB
Chemiosmotic efflux system protein B-like protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.505
Lbru_2740
Hypothetical protein.
  
     0.454
fliH
Polar flagellar assembly protein FliH.
  
     0.431
Lbru_2431
Hypothetical protein.
  
   0.430
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
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