STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
fabF_33-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)    
Predicted Functional Partners:
Lbru_1401
Polyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
0.996
fabD
Malonyl CoA-ACP transacylase.
 0.996
Lbru_2388
Polyketide synthase module.
  
0.990
acpP_1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
 0.983
Lbru_1742
HAD-superfamily phosphatase.
 
 0.968
fabH_1
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.965
Lbru_1743
Polyketide synthase.
 
 0.941
fabZ
(3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 0.934
Lbru_1276
Acetyltransferase.
 
 0.931
Lbru_1462
Polyketide synthase.
  
 0.926
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
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