STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
budB_2Acetolactate synthase. (576 aa)    
Predicted Functional Partners:
Lbru_2780
Acetolactate synthase 3 regulatory subunit.
 
 0.998
dlpA_1
DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.906
leuD
Aconitate hydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.882
leuC
Aconitate hydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.874
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.819
Lbru_0127
4-hydroxy-2-oxovalerate aldolase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.816
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
 0.803
Lbru_2854
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.798
Lbru_0682
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.797
ala_1
D-alanine-aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.793
Your Current Organism:
Legionella brunensis
NCBI taxonomy Id: 29422
Other names: ATCC 43878, CCUG 31114, CIP 103874, DSM 19236, L. brunensis, NCTC 12240, strain 441-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.