| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APR68939.1 | APR68941.1 | AHTJS_00030 | AHTJS_00040 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.481 |
| APR68939.1 | erpA | AHTJS_00030 | AHTJS_00050 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.619 |
| APR68941.1 | APR68939.1 | AHTJS_00040 | AHTJS_00030 | RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.481 |
| APR68941.1 | APR68942.1 | AHTJS_00040 | AHTJS_00045 | RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.690 |
| APR68941.1 | erpA | AHTJS_00040 | AHTJS_00050 | RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.598 |
| APR68942.1 | APR68941.1 | AHTJS_00045 | AHTJS_00040 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.690 |
| APR68942.1 | erpA | AHTJS_00045 | AHTJS_00050 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.747 |
| erpA | APR68939.1 | AHTJS_00050 | AHTJS_00030 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.619 |
| erpA | APR68941.1 | AHTJS_00050 | AHTJS_00040 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.598 |
| erpA | APR68942.1 | AHTJS_00050 | AHTJS_00045 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
| erpA | grpE | AHTJS_00050 | AHTJS_16720 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.414 |
| erpA | grxD | AHTJS_00050 | AHTJS_08505 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Monothiol glutaredoxin, Grx4 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.550 |
| erpA | hscB | AHTJS_00050 | AHTJS_06675 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.570 |
| erpA | iscS | AHTJS_00050 | AHTJS_06690 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.546 |
| erpA | iscU | AHTJS_00050 | AHTJS_06685 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.693 |
| erpA | nfuA | AHTJS_00050 | AHTJS_11290 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.623 |
| grpE | erpA | AHTJS_16720 | AHTJS_00050 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.414 |
| grpE | hscB | AHTJS_16720 | AHTJS_06675 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.405 |
| grpE | nfuA | AHTJS_16720 | AHTJS_11290 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.534 |
| grxD | erpA | AHTJS_08505 | AHTJS_00050 | Monothiol glutaredoxin, Grx4 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.550 |
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