STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APR69434.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)    
Predicted Functional Partners:
pleD_4
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.844
APR69588.1
DNA-binding response regulator PmrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.802
baeR
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.800
APR69458.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.781
tcrA
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.769
APR69571.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.766
APR71677.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.765
glnE
Bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
       0.760
ilvE
Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.733
APR70046.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.727
Your Current Organism:
Acinetobacter haemolyticus
NCBI taxonomy Id: 29430
Other names: A. haemolyticus, ATCC 17906, Achromobacter haemolyticus, Acinetobacter genomosp. 4, Acinetobacter genomospecies 4, Acinetobacter haematolyticus, CCUG 888, CIP 64.3, DSM 6962, LMG 996, LMG:996, NCCB 85026, NCTC 12155, NCTC:12155, strain B40, strain Mannheim 2446/60
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