STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHTJS_14130Xanthine phosphoribosyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.682
APR70732.1
Major capsid protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.626
APR71376.1
Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.552
APR71483.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.542
APR71377.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.517
APR70240.1
Siderophore biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.465
APR71378.1
Heat-shock protein HslJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.439
APR70717.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.437
APR70736.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.427
APR70054.1
Transferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
  
     0.413
Your Current Organism:
Acinetobacter haemolyticus
NCBI taxonomy Id: 29430
Other names: A. haemolyticus, ATCC 17906, Achromobacter haemolyticus, Acinetobacter genomosp. 4, Acinetobacter genomospecies 4, Acinetobacter haematolyticus, CCUG 888, CIP 64.3, DSM 6962, LMG 996, LMG:996, NCCB 85026, NCTC 12155, NCTC:12155, strain B40, strain Mannheim 2446/60
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