STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDH97311.1DNA-binding transcriptional regulator, Lrp family. (153 aa)    
Predicted Functional Partners:
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.779
SDI26876.1
Lrp/AsnC family transcriptional regulator.
  
     0.774
SDH51778.1
DNA-binding transcriptional regulator, Lrp family.
  
     0.773
SDI60207.1
DNA-binding transcriptional regulator, Lrp family.
  
     0.709
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
   
 
 0.672
SDH97279.1
Amino acid efflux transporter.
       0.585
SDH97329.1
Hypothetical protein.
       0.453
SDH97360.1
Hypothetical protein.
       0.453
SDI26893.1
Indolepyruvate ferredoxin oxidoreductase.
    
  0.423
SDH97251.1
Nucleoid-associated protein.
       0.400
Your Current Organism:
Pseudomonas flavescens
NCBI taxonomy Id: 29435
Other names: ATCC 51555, CCUG 49622, CFBP 5586, CIP 104204, DSM 12071, JCM 21586, LMG 18387, LMG:18387, NBRC 103044, NCPPB 3063, P. flavescens, strain B62
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