node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDH62713.1 | SDH96280.1 | SAMN05216588_1069 | SAMN05216588_109136 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Homoserine dehydrogenase. | 0.947 |
SDH62713.1 | SDI23358.1 | SAMN05216588_1069 | SAMN05216588_11390 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.992 |
SDH62713.1 | SDI28018.1 | SAMN05216588_1069 | SAMN05216588_11454 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Aromatic-amino-acid transaminase. | 0.708 |
SDH62713.1 | SDI60053.1 | SAMN05216588_1069 | SAMN05216588_12023 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Homocysteine/selenocysteine methylase (S-methylmethionine-dependent). | 0.727 |
SDH62713.1 | SDI62055.1 | SAMN05216588_1069 | SAMN05216588_12094 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Aminomethyltransferase; Belongs to the GcvT family. | 0.752 |
SDH62713.1 | SDI86727.1 | SAMN05216588_1069 | SAMN05216588_1274 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Aspartate kinase; Belongs to the aspartokinase family. | 0.838 |
SDH62713.1 | metE | SAMN05216588_1069 | SAMN05216588_10771 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.984 |
SDH62713.1 | metG | SAMN05216588_1069 | SAMN05216588_11744 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.812 |
SDH62713.1 | metK | SAMN05216588_1069 | SAMN05216588_10617 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.933 |
SDH62713.1 | metZ | SAMN05216588_1069 | SAMN05216588_101397 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.968 |
SDH96280.1 | SDH62713.1 | SAMN05216588_109136 | SAMN05216588_1069 | Homoserine dehydrogenase. | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | 0.947 |
SDH96280.1 | SDI23358.1 | SAMN05216588_109136 | SAMN05216588_11390 | Homoserine dehydrogenase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.962 |
SDH96280.1 | SDI28018.1 | SAMN05216588_109136 | SAMN05216588_11454 | Homoserine dehydrogenase. | Aromatic-amino-acid transaminase. | 0.820 |
SDH96280.1 | SDI60053.1 | SAMN05216588_109136 | SAMN05216588_12023 | Homoserine dehydrogenase. | Homocysteine/selenocysteine methylase (S-methylmethionine-dependent). | 0.832 |
SDH96280.1 | SDI86727.1 | SAMN05216588_109136 | SAMN05216588_1274 | Homoserine dehydrogenase. | Aspartate kinase; Belongs to the aspartokinase family. | 0.990 |
SDH96280.1 | metE | SAMN05216588_109136 | SAMN05216588_10771 | Homoserine dehydrogenase. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.914 |
SDH96280.1 | metG | SAMN05216588_109136 | SAMN05216588_11744 | Homoserine dehydrogenase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.574 |
SDH96280.1 | metK | SAMN05216588_109136 | SAMN05216588_10617 | Homoserine dehydrogenase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.679 |
SDH96280.1 | metZ | SAMN05216588_109136 | SAMN05216588_101397 | Homoserine dehydrogenase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.943 |
SDI23358.1 | SDH62713.1 | SAMN05216588_11390 | SAMN05216588_1069 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. | 0.992 |