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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (240 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.994
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.954
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.952
pyrB
Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.942
carB
Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family.
 
  
 0.929
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.912
carA
Carbamoyl-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family.
  
  
 0.900
KIU46503.1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
    
  0.886
KIU43130.1
Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.883
KIU45784.1
Dihydropyrimidinase; Catalyzes the hydrolytic cleavage of imides that range from linear to heterocyclic and that include hydantoins, dihydropyrimidines, and phthalimides; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.858
Your Current Organism:
Bradyrhizobium elkanii
NCBI taxonomy Id: 29448
Other names: ATCC 49852, B. elkanii, Bradyrhizobium sp. AK1, Bradyrhizobium sp. AK3, Bradyrhizobium sp. URO14, Bradyrhizobium sp. URO7, Bradyrhizobium sp. mas1, Bradyrhizobium sp. mas10, Bradyrhizobium sp. mas11, Bradyrhizobium sp. mas12, Bradyrhizobium sp. mas17, Bradyrhizobium sp. mas18, Bradyrhizobium sp. mas19, Bradyrhizobium sp. mas20, Bradyrhizobium sp. mas21, Bradyrhizobium sp. mas22, Bradyrhizobium sp. mas23, Bradyrhizobium sp. mas25, Bradyrhizobium sp. mas26, Bradyrhizobium sp. mas27, Bradyrhizobium sp. mas29, Bradyrhizobium sp. mas30, Bradyrhizobium sp. mas31, Bradyrhizobium sp. mas40, Bradyrhizobium sp. mas42, Bradyrhizobium sp. mas6, Bradyrhizobium sp. mas7, Bradyrhizobium sp. mas8, Bradyrhizobium sp. mas9, DSM 11554, IFO 14791, LMG 6134, LMG:6134, NBRC 14791, USDA 76
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