| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIU43145.1 | KIU44106.1 | QU41_34015 | QU41_31155 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.751 |
| KIU43145.1 | KIU49560.1 | QU41_34015 | QU41_11535 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.730 |
| KIU43145.1 | KIU50674.1 | QU41_34015 | QU41_07540 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.751 |
| KIU43145.1 | thyA | QU41_34015 | QU41_30200 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.700 |
| KIU44106.1 | KIU43145.1 | QU41_31155 | QU41_34015 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.751 |
| KIU44106.1 | KIU49560.1 | QU41_31155 | QU41_11535 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
| KIU44106.1 | KIU50088.1 | QU41_31155 | QU41_09505 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.751 |
| KIU44106.1 | KIU50674.1 | QU41_31155 | QU41_07540 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.990 |
| KIU44106.1 | nusB | QU41_31155 | QU41_33450 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.564 |
| KIU44106.1 | thyA | QU41_31155 | QU41_30200 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.547 |
| KIU46385.1 | KIU46698.1 | QU41_22335 | QU41_19965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.838 |
| KIU46385.1 | KIU49560.1 | QU41_22335 | QU41_11535 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.707 |
| KIU46385.1 | folD | QU41_22335 | QU41_08170 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.451 |
| KIU46698.1 | KIU46385.1 | QU41_19965 | QU41_22335 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.838 |
| KIU46698.1 | KIU49560.1 | QU41_19965 | QU41_11535 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.661 |
| KIU46698.1 | folD | QU41_19965 | QU41_08170 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.712 |
| KIU46698.1 | thyA | QU41_19965 | QU41_30200 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.682 |
| KIU49559.1 | KIU49560.1 | QU41_11530 | QU41_11535 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.868 |
| KIU49560.1 | KIU43145.1 | QU41_11535 | QU41_34015 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.730 |
| KIU49560.1 | KIU44106.1 | QU41_11535 | QU41_31155 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |