close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIU49266.12-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)    
Predicted Functional Partners:
KIU49265.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.746
KIU54638.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.736
KIU49264.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH2/MDH2 oxidoreductase family.
    
  0.733
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.655
KIU47634.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.583
KIU52557.1
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.565
KIU43586.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.526
KIU48090.1
5-carboxymethyl-2-hydroxymuconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.509
KIU47741.1
Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.495
fumC1
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.492
Your Current Organism:
Bradyrhizobium elkanii
NCBI taxonomy Id: 29448
Other names: ATCC 49852, B. elkanii, Bradyrhizobium sp. AK1, Bradyrhizobium sp. AK3, Bradyrhizobium sp. URO14, Bradyrhizobium sp. URO7, Bradyrhizobium sp. mas1, Bradyrhizobium sp. mas10, Bradyrhizobium sp. mas11, Bradyrhizobium sp. mas12, Bradyrhizobium sp. mas17, Bradyrhizobium sp. mas18, Bradyrhizobium sp. mas19, Bradyrhizobium sp. mas20, Bradyrhizobium sp. mas21, Bradyrhizobium sp. mas22, Bradyrhizobium sp. mas23, Bradyrhizobium sp. mas25, Bradyrhizobium sp. mas26, Bradyrhizobium sp. mas27, Bradyrhizobium sp. mas29, Bradyrhizobium sp. mas30, Bradyrhizobium sp. mas31, Bradyrhizobium sp. mas40, Bradyrhizobium sp. mas42, Bradyrhizobium sp. mas6, Bradyrhizobium sp. mas7, Bradyrhizobium sp. mas8, Bradyrhizobium sp. mas9, DSM 11554, IFO 14791, LMG 6134, LMG:6134, NBRC 14791, USDA 76
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.