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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIU45842.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.545
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
       0.493
KIU46045.1
Zinc-finger protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.484
KIU45839.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.481
Your Current Organism:
Bradyrhizobium elkanii
NCBI taxonomy Id: 29448
Other names: ATCC 49852, B. elkanii, Bradyrhizobium sp. AK1, Bradyrhizobium sp. AK3, Bradyrhizobium sp. URO14, Bradyrhizobium sp. URO7, Bradyrhizobium sp. mas1, Bradyrhizobium sp. mas10, Bradyrhizobium sp. mas11, Bradyrhizobium sp. mas12, Bradyrhizobium sp. mas17, Bradyrhizobium sp. mas18, Bradyrhizobium sp. mas19, Bradyrhizobium sp. mas20, Bradyrhizobium sp. mas21, Bradyrhizobium sp. mas22, Bradyrhizobium sp. mas23, Bradyrhizobium sp. mas25, Bradyrhizobium sp. mas26, Bradyrhizobium sp. mas27, Bradyrhizobium sp. mas29, Bradyrhizobium sp. mas30, Bradyrhizobium sp. mas31, Bradyrhizobium sp. mas40, Bradyrhizobium sp. mas42, Bradyrhizobium sp. mas6, Bradyrhizobium sp. mas7, Bradyrhizobium sp. mas8, Bradyrhizobium sp. mas9, DSM 11554, IFO 14791, LMG 6134, LMG:6134, NBRC 14791, USDA 76
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