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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIU45350.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (773 aa)    
Predicted Functional Partners:
KIU48337.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.999
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.993
KIU46027.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.993
KIU45831.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.992
KIU50657.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.988
KIU47165.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.988
KIU50786.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.987
KIU45432.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.981
KIU45433.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.977
KIU42882.1
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.977
Your Current Organism:
Bradyrhizobium elkanii
NCBI taxonomy Id: 29448
Other names: ATCC 49852, B. elkanii, Bradyrhizobium sp. AK1, Bradyrhizobium sp. AK3, Bradyrhizobium sp. URO14, Bradyrhizobium sp. URO7, Bradyrhizobium sp. mas1, Bradyrhizobium sp. mas10, Bradyrhizobium sp. mas11, Bradyrhizobium sp. mas12, Bradyrhizobium sp. mas17, Bradyrhizobium sp. mas18, Bradyrhizobium sp. mas19, Bradyrhizobium sp. mas20, Bradyrhizobium sp. mas21, Bradyrhizobium sp. mas22, Bradyrhizobium sp. mas23, Bradyrhizobium sp. mas25, Bradyrhizobium sp. mas26, Bradyrhizobium sp. mas27, Bradyrhizobium sp. mas29, Bradyrhizobium sp. mas30, Bradyrhizobium sp. mas31, Bradyrhizobium sp. mas40, Bradyrhizobium sp. mas42, Bradyrhizobium sp. mas6, Bradyrhizobium sp. mas7, Bradyrhizobium sp. mas8, Bradyrhizobium sp. mas9, DSM 11554, IFO 14791, LMG 6134, LMG:6134, NBRC 14791, USDA 76
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