node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARQ08476.1 | trpS | NXC12_CH00382 | NXC12_CH00383 | Protein involved in response to stress. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.615 |
engD | lepA | NXC12_CH03146 | NXC12_CH00246 | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.837 |
engD | leuS | NXC12_CH03146 | NXC12_CH04280 | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.546 |
engD | metG | NXC12_CH03146 | NXC12_CH02200 | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.658 |
engD | pheT | NXC12_CH03146 | NXC12_CH00263 | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | phenylalanyl-tRNA synthetase subunit beta; Protein involved in nucleotide binding, RNA binding, ATP binding, phenylalanyl-tRNA aminoacylation and tRNA processing; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.860 |
engD | serS | NXC12_CH03146 | NXC12_CH01912 | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.483 |
engD | trpS | NXC12_CH03146 | NXC12_CH00383 | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.634 |
hfq | trpS | NXC12_CH02048 | NXC12_CH00383 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.657 |
lepA | engD | NXC12_CH00246 | NXC12_CH03146 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.837 |
lepA | leuS | NXC12_CH00246 | NXC12_CH04280 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.780 |
lepA | metG | NXC12_CH00246 | NXC12_CH02200 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.447 |
lepA | pheT | NXC12_CH00246 | NXC12_CH00263 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | phenylalanyl-tRNA synthetase subunit beta; Protein involved in nucleotide binding, RNA binding, ATP binding, phenylalanyl-tRNA aminoacylation and tRNA processing; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.551 |
lepA | rplD | NXC12_CH00246 | NXC12_CH01745 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.925 |
lepA | serS | NXC12_CH00246 | NXC12_CH01912 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.488 |
lepA | trpS | NXC12_CH00246 | NXC12_CH00383 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.652 |
lepA | tyrS | NXC12_CH00246 | NXC12_CH02304 | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.573 |
leuS | engD | NXC12_CH04280 | NXC12_CH03146 | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.546 |
leuS | lepA | NXC12_CH04280 | NXC12_CH00246 | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | GTP-binding elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.780 |
leuS | metG | NXC12_CH04280 | NXC12_CH02200 | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.986 |
leuS | pheT | NXC12_CH04280 | NXC12_CH00263 | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase subunit beta; Protein involved in nucleotide binding, RNA binding, ATP binding, phenylalanyl-tRNA aminoacylation and tRNA processing; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.957 |