STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (387 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.997
aroB
aroB: 3-dehydroquinate synthase; [E] COG0337 3-dehydroquinate synthetase.
 
  
 0.990
aroH
CM_mono_aroH: chorismate mutase; [E] COG4401 Chorismate mutase.
  
 
 0.989
trpE
trpE_most: anthranilate synthase component I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 
 0.975
ANB61452.1
trkA-N domain protein; [E] COG0287 Prephenate dehydrogenase.
 
 
 0.947
aroE
aroE: shikimate dehydrogenase; [E] COG0169 Shikimate 5-dehydrogenase.
  
 0.926
pabB
pabB: aminodeoxychorismate synthase, component I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 
 0.909
ANB61633.1
[R] COG4492 ACT domain-containing protein; Belongs to the UPF0735 family.
     
  0.900
GFC30_117
trpG_papA: glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II.
 
 
 0.894
trpA
trpA: tryptophan synthase, alpha subunit; [E] COG0159 Tryptophan synthase alpha chain.
 
  
 0.891
Your Current Organism:
Anoxybacillus amylolyticus
NCBI taxonomy Id: 294699
Other names: A. amylolyticus, ATCC BAA-872, Anoxybacillus amylolyticus Poli et al. 2006, CIP 108338, DSM 15939, strain MR3C
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