STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folEfolE: GTP cyclohydrolase I; [H] COG0302 GTP cyclohydrolase I. (186 aa)    
Predicted Functional Partners:
folK
folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
 0.998
queD
queuosine_QueD: queuosine biosynthesis protein QueD; [H] COG0720 6-pyruvoyl-tetrahydropterin synthase.
  
 
 0.992
folP
DHPS: dihydropteroate synthase; [H] COG0294 Dihydropteroate synthase and related enzymes.
  
 0.987
folB
folB: dihydroneopterin aldolase; [H] COG1539 Dihydroneopterin aldolase.
 
  
 0.975
ribA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.948
moaA
moaA: molybdenum cofactor biosynthesis protein A; [H] COG2896 Molybdenum cofactor biosynthesis enzyme.
    
  0.907
ndk
Nucleoside diphosphate kinase family protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.905
pyk
Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase.
    
  0.814
GFC30_593
Pyruvate kinase, barrel domain protein; [G] COG0469 Pyruvate kinase.
    
  0.807
ANB61861.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.801
Your Current Organism:
Anoxybacillus amylolyticus
NCBI taxonomy Id: 294699
Other names: A. amylolyticus, ATCC BAA-872, Anoxybacillus amylolyticus Poli et al. 2006, CIP 108338, DSM 15939, strain MR3C
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.