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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speE-2Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (275 aa)    
Predicted Functional Partners:
speB
Agmatinase: agmatinase; [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
 
 
 0.993
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
  
 
0.905
mtnN
MTA/SAH-Nsdase: MTA/SAH nucleosidase; [F] COG0775 Nucleoside phosphorylase.
    
 0.901
fliM
fliM_switch: flagellar motor switch protein FliM; [N] COG1868 Flagellar motor switch protein.
    
   0.705
ANB61462.1
Beta-eliminating lyase family protein; [E] COG1982 Arginine/lysine/ornithine decarboxylases.
  
 0.624
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
  0.534
GFC30_319
PBP_1a_fam: penicillin-binding, 1A family protein; [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein).
       0.522
argS
argS: arginine--tRNA ligase; [J] COG0018 Arginyl-tRNA synthetase.
  
    0.512
GFC30_322
Putative membrane protein.
       0.494
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
   
    0.455
Your Current Organism:
Anoxybacillus amylolyticus
NCBI taxonomy Id: 294699
Other names: A. amylolyticus, ATCC BAA-872, Anoxybacillus amylolyticus Poli et al. 2006, CIP 108338, DSM 15939, strain MR3C
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