Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
estCarboxylesterase; [R] COG1647 Esterase/lipase. (245 aa)    
Predicted Functional Partners:
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
  
 0.925
secG
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
     
 0.783
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
     
 0.761
GFC30_310
Biotin/lipoate A/B ligase family protein; [H] COG0095 Lipoate-protein ligase A.
  
     0.732
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
       0.578
ANB60958.1
Iron-sulfur cluster biosynthesis family protein; [S] COG4841 Uncharacterized protein conserved in bacteria.
  
     0.567
ANB61853.1
Cof-sub: Cof-like hydrolase family protein; [R] COG0561 Predicted hydrolases of the HAD superfamily.
      
 0.527
ANB60092.1
[R] COG1286 Uncharacterized membrane protein, required for colicin V production.
  
     0.516
gpmI
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family.
       0.516
pgk
[G] COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
       0.509
Your Current Organism:
Anoxybacillus amylolyticus
NCBI taxonomy Id: 294699
Other names: A. amylolyticus, ATCC BAA-872, Anoxybacillus amylolyticus Poli et al. 2006, CIP 108338, DSM 15939, strain MR3C
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.