STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGUG_01285LMWPc domain-containing protein. (184 aa)    
Predicted Functional Partners:
PGUG_03322
PAPS_reduct domain-containing protein.
    
 0.954
PGUG_02362
Alkaline phosphatase.
    
 0.909
PGUG_05036
Uncharacterized protein.
    
  0.907
FMN1
Riboflavin kinase; Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme; Belongs to the flavokinase family.
    
  0.904
RIB5
Riboflavin synthase; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil.
     
 0.901
PGUG_04644
TMP-TENI domain-containing protein.
    
  0.901
PGUG_01443
Uncharacterized protein; Belongs to the histidine acid phosphatase family.
     
  0.900
PGUG_02670
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
    
  0.900
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
    
 0.849
PGUG_01217
TRANSKETOLASE_1 domain-containing protein.
  
  0.681
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.