STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTRG_00746WD_REPEATS_REGION domain-containing protein. (615 aa)    
Predicted Functional Partners:
CTRG_03626
Actin.
   
 0.902
CTRG_00235
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.850
CTRG_02690
Actin-2; Belongs to the actin family.
   
 0.827
CTRG_01716
Uncharacterized protein; Belongs to the actin family.
   
 0.760
CTRG_00383
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.730
CTRG_01789
Calponin-homology (CH) domain-containing protein.
   
 
 0.704
CTRG_01638
Calponin-homology (CH) domain-containing protein.
   
 0.693
CTRG_05020
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
   
 
  0.614
CTRG_05021
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
   
 
  0.614
CTRG_05955
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.614
Your Current Organism:
Candida tropicalis
NCBI taxonomy Id: 294747
Other names: C. tropicalis MYA-3404, Candida tropicalis MYA-3404, Candida tropicalis T1
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